12 Foreign Stories From 2012 Worth Revisiting

Tyler Hicks/The New York Times

There were hundreds of memorable foreign stories from Times correspondents in 2012. Here is a sampling of 12 from across the world in reverse chronological order

1. For Congo Children, Food Today Means None Tomorrow

KINSHASA, Democratic Republic of Congo — Today, the big children will eat, Cynthia, 15, and Guellor, 13. Tomorrow, it will be the turn of the little ones, Bénédicte, Josiane and Manassé, 3, 6, and 9.

2. Dublin Journal: Not Worth the Paper It’s Built On

DUBLIN — As an emblem of the modern Irish condition, Frank Buckley is almost too apt. Dead broke, he lives in a house made of money.

3. American Children, Now Struggling to Adjust to Life in Mexico

Shaul Schwarz for The New York Times

IZÚCAR DE MATAMOROS, Mexico — Jeffrey Isidoro sat near the door of his fifth-grade classroom here in central Mexico, staring outside through designer glasses that, like his Nike sneakers and Nike backpack, signaled a life lived almost entirely in the United States. His parents are at home in Mexico. Jeffrey is lost.

4. Egypt’s Everywoman Finds Her Place Is in the Presidential Palace

CAIRO — Naglaa Ali Mahmoud wears an Islamic head covering that drapes down to her knees, did not attend college and never took her husband’s last name, because that is a Western convention that few Egyptians follow. She also refuses the title of first lady, in favor of simply Um Ahmed, a traditional nickname that identifies her as the mother of Ahmed, her eldest son.

5. A Superstar Televangelist in Pakistan Divides, Then Repents

Diego Ibarra Sanchez for The New York Times

KARACHI, Pakistan — THE audience erupted as Aamir Liaquat Hussain, Pakistan’s premier televangelist, darted around the television studio, firing off questions about Islam. “How many gates are there to heaven?” he challenged.

6. Elephants Dying in Epic Frenzy as Ivory Fuels Wars and Profits

GARAMBA NATIONAL PARK, Democratic Republic of Congo — In 30 years of fighting poachers, Paul Onyango had never seen anything like this. Twenty-two dead elephants, including several very young ones, clumped together on the open savanna, many killed by a single bullet to the top of the head.

7. Young Lives, Lost in the Fog of War

KABUL, Afghanistan — These days, Abdul Farhad tries to sleep with the lights on in his bedroom and his eyes wide open, because as soon as he closes them he is back in his shop in central Kabul and it is 11:30 a.m. on the eighth of September.

8. Corruption Is Seen as a Drain on Italy’s South

Gianni Cipriano for The New York Times

REGGIO CALABRIA, Italy — Italy’s A3 highway, begun in the 1960s and still not finished, starts outside Naples in the ancient hill town of Salerno and ends, rather unceremoniously, 300 miles farther south as a local street in downtown Reggio Calabria.

9. Reporting a Fearful Rift Between Afghans and Americans

SISAY OUTPOST, Afghanistan — How far is Kabul from the war? These days, if you drive south or west, no more than an hour and a half. You can go and be back for dinner — if you aren’t kidnapped or blown up.

10. Billions in Hidden Riches for Family of Chinese Leader

BEIJING — The mother of China’s prime minister was a schoolteacher in northern China. His father was ordered to tend pigs in one of Mao’s political campaigns. And during childhood, “my family was extremely poor,” the prime minister, Wen Jiabao, said in a speech.

11. Long Retired, Ex-Leader of China Asserts Sway Over Top Posts

BEIJING — In a year of scandals and corruption charges at the commanding heights of the Communist Party, a retired party chief some had written off as a spent force has thrust himself back into China’s most important political decisions and emerged as a dominant figure shaping the future leadership.

12. Horrific Fire Revealed a Gap in Safety for Global Brands

ASHULIA, Bangladesh — The fire alarm shattered the monotony of the Tazreen Fashions factory. Hundreds of seamstresses looked up from their machines, startled. On the third floor, Shima Akhter Pakhi had been stitching hoods onto fleece jackets. Now she ran to a staircase.

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Redskins win NFC East, Broncos get top seed in AFC

RG3 and the Washington Redskins are heading to the playoffs as NFC East champions.

By winning their seventh straight game, the Redskins rolled to their first division title in 13 years with a 28-18 victory over the Dallas Cowboys on Sunday night. Next up for Robert Griffin III & Co.: a home playoff matchup next Sunday with the Seahawks — the third straight postseason game for Washington against Seattle.

"It's just a mindset change," the rookie quarterback said. "When you have all these guys coming to work every day, putting it on the line, we knew we couldn't afford to lose one game, we made sure we didn't"

Thanks to Houston's late-season slump, Denver and New England will have byes when the AFC playoffs begin next week.

The Texans fell from first to third in the conference Sunday when they lost 28-16 at Indianapolis, which welcomed back coach Chuck Pagano after nearly three months of treatments for leukemia.

AFC West champion Denver won its 11th straight game, 38-3 over Kansas City to secure the top seed. New England blanked Miami 28-0 for the second spot.

Minnesota edged Green Bay 37-34 to grab the final NFC wild card, sinking the Packers to the third seed. Those teams will meet again next Saturday night at Lambeau Field.

The other NFC matchup will have Seattle (11-5), which beat St. Louis 20-13, at Washington on Sunday at 4:30 p.m. ET.

Cincinnati (10-6) will be at Houston on Saturday at 4:30 p.m. ET, and Indianapolis (11-5) goes to at Baltimore (10-6) on Sunday at 1 p.m. in the AFC wild-card rounds.

The divisional round games will be hosted by Denver on Saturday, Jan. 12, followed by San Francisco (11-4-1) at night. On Sunday, Jan. 13, Atlanta (13-3) will host the early game, followed by New England (12-4).

Peyton Manning threw for three touchdowns as Denver (13-3) routed the Chiefs. New England got the second seed despite having the same record as Houston because it beat the Texans, who lost three of their final four games.

Adrian Peterson had 199 yards against the Packers, finishing with 2,097 — Dickerson's single-season rushing mark in 2,105. But it was rookie kicker Blair Walsh who won it with a 29-yard field goal as time expired.

"Ultimately we got the 'W,'" Peterson said. "I told myself to come into this game focused on one thing, and that's winning."

Green Bay would have been seeded second in the NFC by beating Minnesota.

"The road got a little tougher having to play on opening weekend, but we've got a home game and that's why you win the division," Aaron Rodgers said. "We get to go back home, and the game will be different. They won't have home-crowd advantage, and hopefully that will make a difference."

Baltimore Pro Bowl safety Ed Reed is looking forward to a reunion with Pagano. He wishes it would come a little later in the postseason.

"Chuck's like a dad to me," Reed said "He means a lot to me. I would have much rather seen them in the AFC championship game than the first game."

But Reed will see him next week at Baltimore.

The Ravens had a chance to move up to the AFC's third seed with a win and a New England loss. But Baltimore lost at Cincinnati as both teams played backups for much of the game.

Pagano coached the Ravens' secondary for three seasons and was promoted to coordinator last year. Players and coaches in Baltimore have kept in touch, offering encouragement as he fought through the cancer treatments.

"Going back to Baltimore, obviously there's some familiarity there," Pagano said. "We had four great years there as a family. It's a top-notch organization, you know, really good football club. It's a great challenge and they have a great team and they have great players all over the place."

The Colts were 2-14 last season and chose quarterback Andrew Luck with the top selection in the draft. Luck and offensive coordinator Bruce Arians, who stepped in as interim coach with Pagano sidelined, led the turnaround.

Next week, Pagano goes up against former boss John Harbaugh.

"I love his family, and he's one of my closest personal friends in coaching," Harbaugh said. "What he's been through is phenomenal, but we're all competitors so that gets set aside."

Houston beat Cincinnati in the opening round of last year's playoffs.

"I think it will be good," said Bengals QB Andy Dalton, who grew up in suburban Houston. "We played there last year and know the atmosphere and what it's going to be like. The experience last year will definitely help us."

The defending Super Bowl champion Giants are out of contention. When Chicago beat Detroit 26-24, the Giants (9-7) were eliminated, even though they routed Philadelphia 42-7.

"It hurts," said Eli Manning. "Each year you want to make the playoffs to give yourself an opportunity to win a championship; 9-7 last year was good enough. It wasn't good enough this year and we knew it wouldn't be."

Minnesota's win eliminated Chicago.

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F.D.A. Approves Sirturo, a New Tuberculosis Drug

The Food and Drug Administration announced on Monday that it had approved a new treatment for multidrug-resistant tuberculosis that can be used as an alternative when other drugs fail.

The drug, to be called Sirturo, was discovered by scientists at Janssen, the pharmaceuticals unit of Johnson & Johnson, and is the first in a new class of drugs that aims to treat the drug-resistant strain of the disease.

Tuberculosis is a highly infectious disease that is transmitted through the air and usually affects the lungs but can also affect other parts of the body, including the brain and kidneys. It is considered one of the world’s most serious public health threats. Although rare in the United States, multidrug-resistant tuberculosis is a growing problem elsewhere in the world, especially in poorer countries. About 12 million people worldwide had tuberculosis in 2011, according to Johnson & Johnson, and about 630,000 had multidrug-resistant TB.

A study in September in The Lancet found that almost 44 percent of patients with tuberculosis in countries like Russia, Peru and Thailand showed resistance to at least one second-line drug, or a medicine used after another drug had already failed.

Treating drug-resistant tuberculosis can take years and can cost 200 times as much as treating the ordinary form of the disease

“This is quite a milestone in the story of therapy for TB,” Dr. Paul Stoffels, the chief scientific officer at Johnson & Johnson, said in an interview. He said the approval was the first time in 40 years that the agency had approved a drug that attacked tuberculosis in a different way from the current treatments on the market. Sirturo works by inhibiting an enzyme needed by the tuberculosis bacteria to replicate and spread throughout the body.

Sirturo, also known as bedaquiline, would be used on top of the standard treatment, which is a combination of several drugs. Patients with drug-resistant tuberculosis often must be treated for 18 to 24 months.

Even as it announced the approval, however, the F.D.A. also issued some words of caution.

“Multidrug-resistant tuberculosis poses a serious health threat throughout the world, and Sirturo provides much-needed treatment for patients who have don’t have other therapeutic options available,” Edward Cox, director of the office of antimicrobial products in the F.D.A.’s center for drug evaluation and research, said in a statement. “However, because the drug also carries some significant risks, doctors should make sure they use it appropriately and only in patients who don’t have other treatment options.”

The consumer advocacy group Public Citizen opposed approval in a letter to the F.D.A. in mid-December, saying that the results of a limited clinical trial showed that patients using bedaquiline were five times as likely to die than those on the standard drug regimen to treat the disease.

“Given that bedaquiline belongs to an entirely new class of drugs, it is entirely feasible that death in some cases was due to some unmeasured toxicity of the drug,” the letter said.

Sirturo carries a so-called black box warning for patients and health care professionals that the drug can affect the heart’s electrical activity, which could lead to an abnormal and potentially fatal heart rhythm. The warning also notes deaths in patients treated with Sirturo. Nine patients who received Sirturo died compared with two patients who received a placebo. Five of the deaths in the Sirturo group and all of the deaths in the placebo arm seemed to be related to tuberculosis, but no consistent reason for the deaths in the remaining Sirturo-treated patients could be identified.

Doctors Without Borders and the Bill and Melinda Gates Foundation, both active in the fight against tuberculosis and other global diseases, applauded the F.D.A.’s decision.

Jan Gheuens, interim director of the TB Program for the Gates Foundation, called it a “long-awaited event” and said the fight against TB had not benefited from new drugs in the way H.I.V. had. Beyond the benefits of the drug itself, he said the quick approval process could be a model for other drugs sorely needed in the developing world.

He also suggested, however, that more trials should be conducted to get a better understanding of the side effects that led to the black box warning.

The F.D.A. approved bedaquiline under an accelerated program that allows the agency to conditionally approve drugs that are viewed as filling unmet medical needs with less than the usual evidence that they work. The drug’s approval was based on studies that showed it killed bacteria more quickly than a control group taking the standard regimen, but it did not measure whether in the end patients actually fared better on bedaquiline. Johnson & Johnson will conduct larger clinical trials to investigate whether the drug performs as predicted.

In a statement responding to Public Citizen’s letter, a spokeswoman for Johnson & Johnson said the company was committed to supporting appropriate use of Sirturo and would “work to ensure Sirturo is used only where treatment alternatives are not available.”

Dr. Stoffels said the hope was that other new tuberculosis drugs would also be approved that, when used in combination with bedaquiline, could shorten and simplify the current standard of treatment. “That is still a long time away,” he acknowledged, but “this is a first step in a new regimen for TB.”

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Big in 2012, but the Future Is Hazy for Bonds

The big story in the markets this year was not about stocks.

Americans sold off their stock mutual funds, the most popular way to invest in American companies, at the fastest clip since 2008, the year the financial crisis began. That occurred despite the fact that the stock market itself rose steadily; the benchmark Standard & Poor’s 500-stock index ended the year up 13.4 percent.

Investors have been opting instead for the assumed safety of bonds. Money has been steadily flowing into mutual funds holding bonds of all sorts for the last four years, but the pace accelerated this year. The percentage of household investments in bonds shot up to 26 percent from 14 percent just five years ago, according to Morningstar.

Entering the new year, a growing number of professional investors are betting that the craze for bonds has gone too far, perhaps dangerously so, as has been evident in the headlines from the year-end reports from large investment firms. “Bond PAIN in 2013?” Wells Capital Management’s chief strategist asked. “Caution: Turn Ahead,” BlackRock analysts wrote. “The inflection year,” said Bank of America.

This is not the first time that analysts have forecast an end to the decades-long rally in bond values. But previously many of the voices predicting it were pessimists who believed that investors would sell off their bonds when they lost faith in the American government’s ability to pay back its bonds, forcing the government and many other bond issuers to pay higher interest rates. When interest rates rise, older bonds with lower interest rates are worth less.

While those previous forecasts have proved expensively wrong, this year the forecasters are being joined by many economic optimists who argue that a strengthening American economy is likely to make investors willing to embrace the risks involved in stocks, luring them out of bonds. The question, they say, is only how quickly it will happen.

“Mathematically, it’s next to impossible to get the kind of returns on bonds you’ve seen over the last few years,” said Kate Moore, the chief global equity strategist at Bank of America.

When the turn does ultimately come, it is likely to cause pain for at least some of the people who have been investing in bonds in recent years.

“You don’t want to be the last one out the door when the trends turn,” said Rebecca H. Patterson, the chief investment strategist at Bessemer Trust. “All good things come to an end and we want to make sure we’re in front of it.”

Most of the talk of investors shifting money from bonds into stocks relies first on the assumption that politicians in Washington are able to resolve the current impasse over the so-called fiscal cliff, the automatic spending cuts and tax increases that will go into effect if Congress and President Obama cannot come to an agreement, and the coming debate over the nation’s debt ceiling. If the political discord continues, it could renew investor attraction to the safety of bonds and put off any shift into stocks.

But a number of surveys suggest that professional investors are already starting to prepare for a change. Hedge funds polled by Bank of America said that they had more of their portfolio allocated to stocks than at any time since 2006.

All but one of the 13 bank strategists tracked by Birinyi Associates expects stock markets to rise in 2013. When 2012 began, the same strategists were predicting a downturn in share prices. Even among mutual fund investors, there are signs that the flows out of stocks and into bonds have been slowing down recently.

The preference for bonds has already been costly for retail investors. Over the last year, most types of American bonds have returned less than an investment in the S.&. P. 500. When inflation is factored in, the benchmark 10-year Treasury security is delivering negative returns.

But many investors are still rattled by the 2008 financial crisis and the turbulence in the stock markets since then, which have led to wild swings. Over the last five years, all major types of American bonds have done better than leading stock indexes.

The Federal Reserve has been engaged in an aggressive effort to buy bonds and drive down interest rates. The long term goal of that program is to encourage banks to lend money and to drive investors out of bonds. But in the meantime, falling interest rates have made bonds more attractive. The Fed has said it wants to keep rates low until 2015, though it could let them rise sooner if the economy picks up faster than expected. The 10-year Treasury hovered near 4 percent in recent years but has stayed below 2 percent for much of 2012.

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IHT Rendezvous: Republicans Consider Changing Electoral Vote Counting to Improve Presidential Odds

WASHINGTON — Not too long ago, political analysts assumed the Republicans had a clear advantage in the Electoral College, the system according to which each state, based on population, is given electors that in almost all cases are awarded on a winner-take-all basis, determining who will be the president of the United States. Today, it’s the Democrats who have the edge.

Page Two

Posts written by the IHT’s Page Two columnists.

Start by looking at the past seven presidential elections, three won by Republicans, four by Democrats. Then put most states that went for one party in five of these seven elections into the red column for Republican, blue for Democrat and purple or toss-up for the others.

Three are caveats: North Carolina and Virginia voted Republican until recently; the trends, however, are so pronounced that they are more purple than red. Conversely, West Virginia voted Democratic in three of these contests, but has moved safely into the red ranks.

BLUE: The District of Columbia and 20 states, mainly on the coasts and in the progressive upper Midwest, with 256 electoral votes, are the Democrats’ base.

RED: 23 states, with 188 electoral votes, including much of the South, the Plains and Rocky Mountains states, are reliably Republican.

There are seven purple states — Florida, Ohio, North Carolina, Virginia, Colorado, Nevada and New Hampshire — with 94 electoral votes.

The upshot: In any normal election cycle, the Republicans have to win Florida and Ohio and at least three of the other five. Or they have to turn around some blue states, such as Pennsylvania and Iowa.

In the my latest Left From Washington, I write about how some Republicans
in states where Republicans control the state government are considering changing how those states assign their electoral votes, instead of the winner-take-all system used in most states, they would emulate Maine and Nebraska, where some of the state’s electoral votes are awarded based on which presidential candidate carried a district.

As I write:

They see a possible test case in Pennsylvania, where Mr. Obama won the popular vote by more than five percentage points, rolling up huge margins in Philadelphia and its suburbs and in Pittsburgh. Mr. Romney, however, carried 13 of the 18 congressional districts. If this new system were in effect, the Republicans would have gotten 13 of the state’s 20 electoral votes while getting trounced in the popular vote. If this occurred in mainly Republican states, it would erase the Democrats’ Electoral College advantage.

Politics do shift. In 1988, the Republicans won California, Michigan, Pennsylvania, New Mexico, Connecticut, Maryland and Vermont; all now are considered safely part of the blue base.

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Purported photo of new BlackBerry phone with QWERTY keyboard leaks

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Adrian Peterson tops 2,000 yards

MINNEAPOLIS (AP) — Adrian Peterson's remarkable comeback season now has a magic number to punctuate it.

Peterson became the seventh player to rush for 2,000 yards in a season, plowing through the Green Bay Packers for a 20-yard gain that put him over the top in the third quarter Sunday.

Peterson entered the game needing 102 yards to join O.J. Simpson, Eric Dickerson, Barry Sanders, Terrell Davis, Jamal Lewis and Chris Johnson in the 2,000-yard club. Peterson is the only one to do it after reconstructive knee surgery.

Dickerson's single-season record of 2,105 yards set in 1984 isn't far out of reach, either. Peterson needed 208 yards when the day began, and was 64 yard away as the fourth quarter approached.

The Vikings punted a few plays after Peterson's big run, and the crowd gave him a standing ovation when the achievement was announced. Peterson took it all in stride, waving politely, but otherwise not making anything special out of it in a game the Vikings needed to win to make the playoffs. He simply didn't have time to reflect on the long, arduous path it took for him to get there after tearing the ACL in his left knee.

It was only last December when Peterson crumpled to the turf in Washington, two ligaments torn, leaving many to wonder if his career would ever be the same.

Well, it hasn't been.

Peterson vowed from the very beginning to return better than ever from an injury that has ended the careers of so many before him. There weren't many believers, including in his own locker room.

But a combination of uncommon genetics, unshakable determination and a smart rehabilitation plan from Vikings athletic trainer Eric Sugarman had Peterson back in the starting lineup on opening day.

Peterson scored two touchdowns in the opener, but didn't top 100 yards in a game until Week 4 when he went for 102 against the Lions. As the season went on, the scar tissue in his knee started to break up and Peterson took off like a purple rocket.

His cuts are sharper, his vision better, his patience is making the difference between a 4-yard plunge through the line and a 40-yard dash down the sideline.

He went on a breathtaking eight-game run, amassing 1,313 yards and topping 200 yards twice in four games to vault into the MVP discussion and make 2,000 yards a possibility.

When asked this week to describe his running style in one word, Peterson replied: "Vicious."

That certainly sums it up.

He got off to a fast start with 61 yards and a touchdown on the first two drives, hearing chants of "MVP! MVP!" just before he surged into the end zone for a 7-yard score and a 10-0 Vikings lead. He also had runs of 12 and 21 yards early to get the Vikings going in this win-and-they're-in game.

The Vikings have followed Peterson's lead, needing a victory over the Packers on Sunday to get into the playoffs in what most observers expected to be a rebuilding year. Peterson has carried the offense on his broad shoulders, turning the Vikings into a throwback attack that relies almost exclusively on the run for its big plays.

With second-year quarterback Christian Ponder going through some highs and lows, and the Vikings missing top receiver Percy Harvin with an ankle injury, the passing offense has ranked last in the league. Peterson is averaging more yards per rush than Ponder does per pass and his seven rushes of 50 yards tied him with Sanders in 1997 for the NFL record.

All the while, Peterson has said he'd take the first postseason berth in three years over 2,000 yards any day. But it was no secret that the individual achievement was important to him.

Unlike baseball, the NFL has few numbers that immediately grab the public's attention. One of those is 2,000 yards, especially in this new pass-happy league. Peterson entered the game with 1,898 yards, more than 400 better than Seattle's Marshawn Lynch, who was in second place.

"I definitely want to keep the running backs highlighted," Peterson said this week. "It's started to turn into more of a spread, quarterback-friendly NFL. But just keep letting them know that there are going to be running backs that can do this."

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Online: http://pro32.ap.org/poll and http://twitter.com/AP_NFL

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Questcor Finds Profit for Acthar Drug, at $28,000 a Vial

Kevin Moloney for The New York Times

Christina Culver with her son Tyler, 6, at home in Colorado Springs this month. In 2007, Tyler was hospitalized when the price of Acthar soared.

THE doctor was dumbfounded: a drug that used to cost $50 was now selling for $28,000 for a 5-milliliter vial.

The physician, Dr. Ladislas Lazaro IV, remembered occasionally prescribing this anti-inflammatory, named H.P. Acthar Gel, for gout back in the early 1990s. Then the drug seemed to fade from view. Dr. Lazaro had all but forgotten about it, until a sales representative from a company called Questcor Pharmaceuticals appeared at his office and suggested that he try it for various rheumatologic conditions.

“I’ve never seen anything like this,” Dr. Lazaro, a rheumatologist in Lafayette, La., says of the price increase.

How the price of this drug rose so far, so fast is a story for these troubled times in American health care — a tale of aggressive marketing, questionable medicine and, not least, out-of-control costs. At the center of it is Questcor, which turned the once-obscure Acthar into a hugely profitable wonder drug and itself into one of Wall Street’s highest fliers.

At least until recently, that is. Now some doctors, insurance companies and investors are beginning to have doubts about whether the drug is really any better than much cheaper alternatives. Short-sellers have written scathing criticisms of the company, questioning its marketing tactics and predicting that its shareholders are highly vulnerable.

 That Acthar is even a potential blockbuster is a remarkable turn of events, considering that the drug was developed in the 1950s by a division of Armour & Company, the meatpacking company that once ruled the Union Stock Yards of Chicago. As in the 1950s, Acthar is still extracted from the pituitary glands of slaughtered pigs — essentially a byproduct of the meatpacking industry.

The most important use of Acthar has been to treat infantile spasms, also known as West syndrome, a rare, sometimes fatal epileptic disorder that generally strikes before the age of 1.

For several years, Questcor, which is based in Anaheim, lost money on Acthar because the drug’s market was so small. In 2007, it raised the price overnight, to more than $23,000 a vial, from $1,650, bringing the cost of a typical course of treatment for infantile spasms to above $100,000. It said it needed the high price to keep the drug on the market.

“We have this drug at a very high price right now because, really, our principal market is infantile spasms,” Don M. Bailey, Questcor’s chief executive, told analysts in 2009. “And we only have about 800 patients a year. It’s a very, very small — tiny — market.”

Companies often charge stratospheric prices for drugs for rare diseases — known as orphan drugs — and Acthar’s price is not as high as some. Society generally tolerates those costs to encourage drug companies to develop crucial, possibly lifesaving drugs for these often neglected diseases.

But Questcor did almost no research or development to bring Acthar to market, merely buying the rights to the drug from its previous owner for $100,000 in 2001. And while the manufacturing of Acthar is complex, it accounts for only about 1 cent of every dollar that Questcor charges for the drug.

Moreover, the tiny “orphan” market soon became much bigger. Before long, Questcor began marketing the drug for multiple sclerosis, nephrotic syndrome and rheumatologic conditions, even though there is little evidence that Acthar is more effective for those other conditions than alternatives that are far cheaper. And the company did so without being required to prove that the drug actually works. That is because Acthar was approved for use in 1952, before the Food and Drug Administration required clinical trials to show a drug is effective for a particular disease. Acthar is essentially grandfathered in.

Today, only about 10 percent of the drug’s sales are for infantile spasms. The new uses, Mr. Bailey has told analysts, represent multibillion-dollar opportunities for Acthar and Questcor, its sole maker.

The results have been beyond even the company’s wildest dreams. Sales of Acthar, which accounts for essentially all of Questcor’s sales, totaled nearly $350 million in the first nine months this year, up 145 percent from the period a year earlier. In the same period, Questcor’s earnings per share nearly tripled, to $2.12. In the five years after the big Acthar price increase in August 2007, Questcor shares rose from around 60 cents to about $50, in one of the best performances of any stock in any industry.

But in September, the shares plummeted after Aetna, the big insurer, said it would no longer pay for Acthar, except to treat infantile spasms, because of lack of evidence the drug worked for other diseases. The stock now trades at $26.93.

Peter Wickersham, senior vice president for cost of care at Prime Therapeutics, a pharmacy benefits manager that has found the drug is possibly being overused, says the huge increase in Acthar’s price for patients “just invites the type of scrutiny that it’s received.”

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IHT Rendezvous: The Rope, the App and Van Gogh in Amsterdam

AMSTERDAM—Consolation for disappointed art lovers who arrive in this city and realize that the Van Gogh Museum is closed for renovation: Follow the red braided rope.

It’s affixed to the corner of the old museum building, leading away from the construction site and stretches to Museumplein, Amsterdam’s great museum square.

The red rope is part of Amsterdam’s most public Van Gogh installation, the Van Gogh Mile. In place until the Van Gogh Museum reopens in spring 2013, it connects the Van Gogh museum with the site of the temporary Van Gogh exhibition, the Hermitage museum, 2.2 kilometers across the historic center of Amsterdam.  The rope is the most visible part of a multidisciplinary art walk designed by Henk Schut for the Van Gogh Museum. The walk guides would-be visitors through Van Gogh’s life, thoughts and travels, while directing them to his famous paintings.

“By following the rope, you can let go and you can trust us,” said Mr. Schut, whose installation is inspired by the 900 letters Vincent Van Gogh wrote to his brother, Theo.

A Van Gogh Mile app can be downloaded from a free WiFi spot close to the start of the tour and is supported by iPhones, iPads and Android-based phones.

The first digital installment of the tour is activated at the head of the fountain basin on the Museum Square, just in front of the “IamAmsterdam” sign.  A tap on the device and the same place appears on the screen. As if looking through a camera, the monuments and buildings of the Museumplein move as the user moves the device. A sweep of the device downward shows the scene as an expanse of sunflowers in bloom.

“There are moments of poetic license to synthesize, to be inspired by his letters,” said Mr. Schut.

The augmented reality software transposes the courtyard of an old sanitarium in the south of France where Van Gogh spent some time into the inner courtyard of the Hermitage museum.

At a stop along the route in front of the Rijkmuseum, the user flies (with the help of their digital device and some imagination) through an open window to see a Rembrandt painting. An audio clip of a reading of one of the artist’s letters describing his reaction to Rembrandt’s art comes through the headphones.

The audio for the tour is all from Van Gogh’s letters, and is in either English or Dutch. Rather than explain the visual experiences, the snippets provide atmosphere.

David Kat, who co-created the app, describes Van Gogh’s letters used in the tour as “handwritten, sketch-like, quick thoughts.”

A third component of the tour ensures that not only smart-phone users benefit from the Van Gogh Mile. Loudspeakers hanging from trees, posts and house-fronts along the rope’s route broadcast more of Van Gogh’s letters. Other public installations, such as a picture frame bearing one of Van Gogh’s musings about art near the Amstel Church, are strewn along the path to be discovered by those who take their time in looking around.  By having walkers looking upward at a rope instead of downward at a map, Mr. Schut hopes to make the audience discover Amsterdam the way Van Gogh himself would have on his many solitary walks.

“It is a connection between looking and walking,” said Mr. Schut.

The detour from the Van Gogh Museum to the Van Gogh art at the Hermitage Museum, with its fragmented audio, fantastical images and physical installations is designed to inspire engagement with the artist, not provide biographical information on his life, explained Mr. Schut.

There are already plenty of sources for that.

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Facebook Instagram use dived after photo fiasco: AppData

SAN FRANCISCO (Reuters) – Facebook Inc’s Instagram lost almost a quarter of its daily users a week after it rolled out and then withdrew policy changes that incensed users who feared the photo-sharing service would use their pictures without compensation.

Instagram, which Facebook bought for $ 715 million this year, saw the number of daily active users who accessed the service via Facebook bottom out at 12.4 million as of Friday, versus a peak of 16.4 million last week, according to data compiled by online tracker AppData.

The popular app, which allows people to add filters and effects to photos and share them over the Internet or smartphones, experienced the drop over the brief, often-volatile holiday period.

Other popular apps also saw slippage in usage, and some were more pronounced. Yelp, for instance, saw daily active users — again via Facebook — slide to a weekly low of half a million on Thursday, from a high of 820,000 one week ago.

Instagram disputed the AppData survey, which was compiled from users that have linked the photo service to their own Facebook accounts, historically between 20 and 30 percent of Instagram members.

“This data is inaccurate. We continue to see strong and steady growth in both registered and active users of Instagram,” a spokeswoman said in an emailed statement on Friday.

Looking out over a broader timeframe, Instagram’s monthly active users edged up to 43.6 million as of Friday, an increase of 1.7 million over the past seven days, according to AppData.

“We’ll have to monitor the data over the coming weeks to gain perspective on trends in Instagram’s performance,” AppData marketing manager Ashley Taylor Anderson said in an email.

ATTENTION-SEEKING

The sharp slide in activity highlighted by AppData was bound to draw attention on the heels of the controversial revision to Instagram’s terms of service that, among other things, allowed an advertiser to pay Instagram “to display your username, likeness, photos (along with any associated metadata)” without compensation.

The subsequent public outrage prompted an apology from Instagram founder Kevin Systrom. Last week, a California Instagram user sued the company for breach of contract and other claims, in what may have been the first civil lawsuit to stem from the controversial change.

Instagram subsequently reverted to some of its original language.

The move renewed debate about how much control over personal data users must give up to live and participate in a world steeped in social media.

Analysts say Facebook, the world’s largest social network, was laying the groundwork to begin generating advertising revenue, by giving marketers the right to display profile pictures and other personal information, such as who users follow in advertisements.

Its shares closed down 13 cents or 0.5 percent at $ 25.91 on the Nasdaq, in line with the broader market.

(Reporting By Edwin Chan; Editing by Leslie Adler and Andrew Hay)

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NHL makes new offer; lockout enters critical stage

NEW YORK (AP) — The NHL made a new offer to the players' association, hoping to spark talks toward ending the long lockout and saving the hockey season.

Deputy commissioner Bill Daly said Friday the league presented its proposal Thursday and was waiting for a response. The sides haven't met in person since a second round of talks with a federal mediator broke down Dec. 13.

The lockout has reached its 104th day, and the NHL said it doesn't want a season of less than 48 games. That means a deal would need to be reached mid-January.

"We delivered to the union a new, comprehensive proposal for a successor CBA," Daly said in a statement Friday. "We are not prepared to discuss the details of our proposal at this time. We are hopeful that once the union's staff and negotiating committee have had an opportunity to thoroughly review and consider our new proposal, they will share it with the players. We want to be back on the ice as soon as possible."

A person familiar with key points of the offer told The Associated Press that the league proposed raising the limit of individual free-agent contracts to six years from five — seven years if a team re-signs its own player; raising the salary variance from one year to another to 10 percent, up from 5 percent; and one compliance buyout for the 2013-14 season that wouldn't count toward a team's salary cap but would be included in the overall players' share of income.

The person spoke on condition of anonymity because details of the new offer were not being discussed publicly.

The NHL maintained the deferred payment amount of $300 million it offered in its previous proposal, an increase from an earlier offer of $211 million. The initial $300 million offer was pulled off the table after negotiations broke off earlier this month.

The latest proposal is for 10 years, running through the 2021-22 season, with both sides having the right to opt out after eight years.

A conference call with the players' association's negotiating committee and its executive board was scheduled for Friday afternoon and was expected to last several hours.

The lockout has reached a critical stage, threatening to shut down a season for the second time in eight years. All games through Jan. 14, plus the Winter Classic and the All-Star game already have been called off. The next round of cuts could claim the entire schedule.

The NHL is the only North American professional sports league to cancel a season because of a labor dispute, losing the 2004-05 campaign to a lockout. A 48-game season was played in 1995 after a lockout stretched into January.

It is still possible this dispute could eventually be settled in the courts if the sides can't reach a deal on their own.

The NHL filed a class-action suit this month in U.S. District Court in New York in an effort to show its lockout is legal. In a separate move, the league filed an unfair labor practice charge with the National Labor Relations Board, contending bad-faith bargaining by the union.

Those moves were made because the players' association took steps toward potentially filing a "disclaimer of interest," which would dissolve the union and make it a trade association. That would allow players to file antitrust lawsuits against the NHL.

Union members voted overwhelmingly to give their board the power to file the disclaimer by Jan. 2. If that deadline passes, another authorization vote could be held to approve a later filing.

Negotiations between the NHL and the union have been at a standstill since talks ended Dec. 6. One week later, the sides convened again with federal mediators in New Jersey, but still couldn't make progress.

The sides have been unable to reach agreement on the length of the new deal, the length of individual player contracts, and the variance in salary from year to year. The NHL is looking for an even split of revenues with players.

The NHL pulled all previous offers off the table after the union didn't agree to terms on its last proposal without negotiation.

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Surgery Returns to NYU Langone Medical Center

Chang W. Lee/The New York Times

Senator Charles E. Schumer spoke at a news conference Thursday about the reopening of NYU Langone Medical Center.

NYU Langone Medical Center opened its doors to surgical patients on Thursday, almost two months after Hurricane Sandy overflowed the banks of the East River and forced the evacuation of hundreds of patients.

While the medical center had been treating many outpatients, it had farmed out surgery to other hospitals, which created scheduling problems that forced many patients to have their operations on nights and weekends, when staffing is traditionally low. Some patients and doctors had to postpone not just elective but also necessary operations for lack of space at other hospitals.

The medical center’s Tisch Hospital, its major hospital for inpatient services, between 30th and 34th Streets on First Avenue, had been closed since the hurricane knocked out power and forced the evacuation of more than 300 patients, some on sleds brought down darkened flights of stairs.

“I think it’s a little bit of a miracle on 34th Street that this happened so quickly,” Senator Charles E. Schumer of New York said Thursday.

Mr. Schumer credited the medical center’s leadership and esprit de corps, and also a tour of the damaged hospital on Nov. 9 by the administrator of the Federal Emergency Management Agency, W. Craig Fugate, whom he and others escorted through watery basement hallways.

“Every time I talk to Fugate there are a lot of questions, but one is, ‘How are you doing at NYU?’ ” the senator said.

The reopening of Tisch to surgery patients and associated services, like intensive care, some types of radiology and recovery room anesthesia, was part of a phased restoration that will continue. Besides providing an essential service, surgery is among the more lucrative of hospital services.

The hospital’s emergency department is expected to delay its reopening for about 11 months, in part to accommodate an expansion in capacity to 65,000 patient visits a year, from 43,000, said Dr. Andrew W. Brotman, its senior vice president and vice dean for clinical affairs and strategy.

In the meantime, NYU Langone is setting up an urgent care center with 31 bays and an observation unit, which will be able to treat some emergency patients. It will initially not accept ambulances, but might be able to later, Dr. Brotman said. Nearby Bellevue Hospital Center, which was also evacuated, opened its emergency department to noncritical injuries on Monday.

Labor and delivery, the cancer floor, epilepsy treatment and pediatrics and neurology beyond surgery are expected to open in mid-January, Langone officials said. While some radiology equipment, which was in the basement, has been restored, other equipment — including a Gamma Knife, a device using radiation to treat brain tumors — is not back.

The flooded basement is still being worked on, and electrical gear has temporarily been moved upstairs. Mr. Schumer, a Democrat, said that a $60 billion bill to pay for hurricane losses and recovery in New York and New Jersey was nearing a vote, and that he was optimistic it would pass in the Senate with bipartisan support. But the measure’s fate in the Republican-controlled House is far less certain.

The bill includes $1.2 billion for damage and lost revenue at NYU Langone, including some money from the National Institutes of Health to restore research projects. It would also cover Long Beach Medical Center in Nassau County, Bellevue, Coney Island Hospital and the Veterans Affairs hospital in Manhattan.

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Obama to Urge Fiscal Vote in Senate if Two-Party Talks Fail

Luke Sharrett for The New York Times

In a televised statement at the White House after meeting with Congressional leaders on Friday, President Obama said he was “modestly optimistic” that an agreement could be reached.

WASHINGTON — President Obama said Friday evening that progress had been made in make-or-break talks on the fiscal crisis and pronounced himself cautiously “optimistic,” as Senate leaders worked furiously toward an agreement to avert the worst of the economic punch from landing Jan. 1.

But after a one-hour meeting with Congressional leaders at the White House, Mr. Obama warned that if the two sides did not agree on a bill, he would urge the Democratic-controlled Senate to put forward a measure anyway, in essence daring Republicans in the House and Senate to block a floor vote on tax cuts.

“I believe such proposals could pass both houses with a bipartisan majority as long as both leaders will allow it to come to a vote,” Mr. Obama said. “If members want to vote no, they can.”

Senators broke from a long huddle on the Senate floor with Senator Mitch McConnell of Kentucky, the Republican leader, to say progress had been made. Mr. McConnell, White House aides, and Senator Harry Reid of Nevada, the majority leader, were set to continue talks on Saturday aiming for a breakthrough as soon as Sunday.

“We’re working with the White House, and hopefully we’ll come up with something we can recommend to our respective caucuses,” Mr. McConnell told reporters.

Mr. Reid also said that there had been some progress but he warned that in assembling a measure that can win support from both parties, “what we come up with is going to be imperfect.”

For all the cautious optimism, the president also expressed exasperation that four days before a looming deadline, which lawmakers have known about for a year and a half, the two sides are still far apart.

“This is déjà vu all over again,” he said. “America wonders why it is that in this time, you can’t get stuff done in an organized timetable. The American people are not going to have any patience for a politically self-inflicted wound to our economy.”

Mr. Obama took steps to keep the pressure on throughout the weekend, scheduling an appearance on Sunday’s “Meet the Press” on NBC.

The emerging path to a possible resolution, at least Friday, appeared to mirror the protracted stalemate over the payroll tax cut last year. In that conflict, House Republicans refused to go along with a short-term extension of the cut, but Mr. McConnell struck a deal that permitted such a measure to get through the Senate, and Speaker John A. Boehner essentially forced members of the House to accept it from afar, after members had left for Christmas recess.

This time, the consequences are even more significant, with more than a half-trillion dollars of tax increases and across-the-board spending cuts just days from going into force, an event most economists warn would send the economy back into recession if not quickly reversed. With the House set to return to the Capitol on Sunday, Mr. Boehner has said he would place any Senate-passed bill before his chamber — perhaps amended — and let the chips fall, with or without Republicans on board.

“I’ve got a positive feeling now,” said Senator Kay Bailey Hutchison, Republican of Texas, who said a burst of deal-making talk broke out as soon as the leaders returned to the Capitol.

This was the first time in weeks that Mr. Obama met with the four Congressional leaders — Mr. Reid, Mr. McConnell, Mr. Boehner and Representative Nancy Pelosi, the Democratic leader.

The meeting started with the president reiterating his demand for an extension of tax cuts on incomes below $250,000.

That opening offer lowered expectations on Capitol Hill that a breakthrough could be pending, but behind the scenes, talks continued, focusing on a possibly higher threshold of $400,000. Senator Max Baucus of Montana, chairman of the Senate Finance Committee, said sentiment is “jelling” around a new offer, and a source familiar with the negotiations said the president would ask Republican and Democratic leaders what proposal could win majority support in the House and Senate.

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Putin to Sign Ban on U.S. Adoptions of Russian Children

MOSCOW — President Vladimir V. Putin said Thursday that he would sign into law a bill banning adoptions of Russian children by American citizens, retaliating against a new American law that seeks to punish human rights abuses in Russia and dealing a serious blow to bilateral relations after a year in which ties have become increasingly strained.

Most immediately, though, the ban stands to upend the plans of dozens of American families in the final stages of adopting children in Russia, adding wrenching emotional tumult to a process that can cost $50,000 or more, requires repeated trips overseas, and even under the best of circumstances typically entails lengthy and maddening bureaucracy.

Although his decision has been eagerly awaited, Mr. Putin seemed rather blasé at a meeting with senior government officials on Thursday that included cabinet members, legislative leaders and governors. When Vladimir S. Gruzdev, the governor of the Tula region, said, “I would like to ask, what is the fate of the law?” Mr. Putin replied curtly, “Which law?”

The adoption ban, included in a broader law aimed at retaliating against the United States, was approved unanimously by the Federation Council, the upper chamber of Parliament, on Wednesday. Mr. Putin went on to say that he would sign the bill and a decree also adopted on Wednesday, calling for improvements in Russia’s child welfare system.

“I intend to sign the law,” Mr. Putin said, “as well as a presidential decree changing the procedure of helping orphaned children, children left without parental care, and especially children who are in a disadvantageous situation due to their health problems.”

Mr. Putin also brushed aside criticism that the law would deny some Russian orphans the chance for a much better life in the United States. In 2011, about 1,000 Russian children were adopted to America, more than to any other foreign country, but still a tiny number given that nearly 120,000 children in Russia are eligible for adoption.

“There are probably many places in the world where living standards are better than ours,” Mr. Putin said. “So what? Shall we send all children there, or move there ourselves?”

United States officials have strongly criticized the measure and have urged the Russian government not to enmesh orphaned children in politics. “We have repeatedly made clear, both in private and in public, our deep concerns about the bill passed by the Russian Parliament,” a State Department spokesman, Patrick Ventrell, said on Thursday. “Since 1992 American families have welcomed more than 60,000 Russian children into their homes, and it is misguided to link the fate of children to unrelated political considerations.”

Internally, however, Obama administration officials have been engaged in a debate over how strongly to respond to the adoption ban, and how to assess the potential implications for other aspects of the country’s relationship with Russia.

The United States, for instance, now relies heavily on overland routes through Russia to ship supplies to military units in Afghanistan, and has enlisted Russia’s help in containing Iran’s nuclear program. The former cold war rivals also have sharp disagreements, notably over the civil war in Syria.

And with the White House and Congress heavily focused on the fiscal debate in Washington, there seems to be little room for developing a more forceful response on the adoption issue.

The news led to shock and despair among the hundreds of American families waiting to adopt a Russian child.

“I’m a little numb,” said Maria Drewinsky, a massage therapist from Sea Cliff, N.Y., who was in the final stages of adopting Alyosha, 5, has flown twice to visit him and speaks to him weekly on the telephone. “We have clothes and a bedroom all set up for him, and we talk about him all the time as our son.”

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750,000 Android apps invade OS X thanks to BlueStacks App Player

Earlier this year, BlueStacks App Player made headlines by allowing Android apps run on Microsoft’s (MSFT) Windows 8 platform. The company announced on Thursday its App Player is now available in beta form for free on Mac, giving OS X users access to 750,000 Android apps normally reserved for smartphones and tablets.

[More from BGR: Google names 12 best Android apps of 2012]

BlueStacks uses patent-pending virtualization software called “Layercake” to allow Android apps to run on other platforms. It works virtually the same as running Windows within OS X using software such as Parallels or VMWare. The Windows 8 version of BlueStacks has been out since March and has been installed on more than 5 million PCs, which is a good sign that people want to run mobile apps on their computers.

[More from BGR: Samsung looks to address its biggest weakness in 2013]

BGR tested BlueStacks on a mid-2011 MacBook Air running OS X 10.8 Mountain Lion and found performance to be hit or miss. Android apps can be searched and it will list which app stores to download them from, but sometimes apps won’t install properly because of missing code, especially from the Google Play store. Downloading apps from the Amazon (AMZN) Appstore seems to be a better bet, though. If it’s any consolation, Jetpack Joyride and Fruit Ninja are perfectly playable.

BlueStacks works as mostly advertised, but honestly, why bother running Android apps on your Mac? A mouse or trackpad isn’t a better substitute for a touchscreen. But if you must do so, it’s reassuring to know BlueStacks is available.

This article was originally published by BGR

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Net loss: Brooklyn fires coach Avery Johnson

NEW YORK (AP) — Coach of the month in November, out of a job by New Year's.

The Brooklyn Nets have elevated expectations this season, and a .500 record wasn't good enough. Coach Avery Johnson was fired Thursday, his team having lost 10 of 13 games after a strong start to its first season in Brooklyn.

"We don't have the same fire now than we did when we were 11-4," general manager Billy King said at a news conference in East Rutherford, N.J. "I tried to talk to Avery about it and we just can't figure it out. The same pattern kept on happening."

Assistant P.J. Carlesimo will coach the Nets on an interim basis, starting Friday night with a home game against Charlotte. King said the Nets might reach out to other candidates, but for now the job was Carlesimo's. The GM wouldn't comment on a report that the team planned to get in touch with former Lakers coach Phil Jackson.

King said the decision to dismiss Johnson was made by ownership after a phone discussion Thursday morning. Owner Mikhail Prokhorov had expressed faith in Johnson before the season.

"With the direction we were going we felt we had to make a change," King said.

Johnson was in the final year of a three-year, $12 million contract.

"It's a really disappointing day for me and my family. It's my wife's birthday. It's not a great birthday gift," Johnson said. "I didn't see this coming. But this is ownership's decision. It's part of the business. Fair or unfair, it's time for a new voice and hopefully they'll get back on track."

The Nets have fallen well behind the first-place New York Knicks, the team they so badly want to compete with in their new home. But after beating the Knicks in their first meeting Nov. 26, probably the high point of Johnson's tenure, the Nets went 5-10 and frustrations have been mounting.

"Our goal is to get to the conference finals," King said. "We started out good and then we stumbled. We have to get back to playing winning basketball. It's the entire team. It's not like golf, where Tiger Woods can blame the caddie. It takes five guys on the court and they're all struggling. We have to figure out the ways to get back to winning. I don't know what happened. I'm not sure. But unfortunately, it did happen."

The Nets were embarrassed by Boston on national TV on Christmas, then were routed by Milwaukee 108-93 on Wednesday night for their fifth loss in six games.

Star guard Deron Williams recently complained about Johnson's offense, and Nets CEO Brett Yormark took to Twitter after the loss to Celtics to voice his displeasure with the performance.

King said the change was not made because Williams was unhappy, and he added the point guard himself has to play better.

Johnson also stood by Williams.

"From Day One, I always had a really good relationship with him. I don't think it's fair for anyone to hang this on Deron," Johnson said. "We were just going through a bad streak, a bad spell. It's not time for me to be down on one player. That would be the easy way."

Brooklyn started the season 11-4, winning five in a row to end November, when Johnson was Eastern Conference coach of the month. But he couldn't do anything to stop this slump, one the Nets never anticipated after a $350 million summer spending spree they believed would take them toward the top of their conference.

Johnson has been the Nets' coach for a little more than two seasons. He went 60-116 with the Nets, who moved from New Jersey to Brooklyn to start the season. Johnson coached the Dallas Mavericks to a spot in the NBA Finals in 2006.

"You don't always get a fair shake as a coach," Johnson said. "I'm not the owner. If I were the owner, I wouldn't have fired myself today. But life is not always necessary fair. It's a business and in this business, the coach always gets blamed."

This is the NBA's second coaching change this season following the dismissal of Mike Brown by the Los Angeles Lakers.

Johnson arrived in New Jersey with a 194-70 record, a .735 winning percentage that was the highest in NBA history, but had little chance of success in his first two seasons while the Nets focused all their planning on the move to Brooklyn.

They looked to make a splash this summer when they re-signed Williams and fellow starters Gerald Wallace, Brook Lopez and Kris Humphries, traded for Atlanta All-Star Joe Johnson, and added veteran depth with players such as Reggie Evans, C.J. Watson and Andray Blatche.

Johnson didn't have a contract beyond this season but seemed to have the confidence of Prokhorov, the Russian billionaire who before the season said he had faith in "the Avery defense system."

Some thought the Nets would finish as high as second in the East behind defending champion Miami, and the predictions seemed warranted when the Nets started quickly amid much fanfare. But all the good publicity faded in recent weeks once the losing started.

Williams, who has struggled this season, stirred the waters when he expressed his preference for the offense he ran under Jerry Sloan in Utah before a loss to the Jazz. Williams and Johnson, nicknamed "Brooklyn's Backcourt" and expected to be one of the best in the NBA, have shot poorly and rarely meshed.

The Nets were embarrassed near the end of their 93-76 loss to Boston, when fans exited early amid a chant of "Let's go Celtics!"

"Nets fans deserved better," Yormark tweeted after the game. "The entire organization needs to work harder to find a solution. We will get there."

Not under Johnson, though.

The Nets should be able to entice a big-name coach with Prokhorov's billions and the chance to play in a major market at Barclays Center, the $1 billion arena that has drawn praise in the city and from visiting teams.

Carlesimo has previous NBA head coaching experience in Portland, Golden State and Seattle/Oklahoma City. He has a career coaching record of 204-296 in the regular season and 3-9 in the playoffs.

"Right now, P.J. is our coach and I told him to coach the team like he'll be here for the next 10 years," King said.

___

AP Sports Writer Tom Canavan in East Rutherford and AP freelancer Jim Hague contributed to this report.

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7-Eleven Stores Focus on Healthier Food Options

The chain that is home of the Slurpee, Big Gulp and self-serve nachos with chili and cheese is betting that consumers will stop in for yogurt parfaits, crudité and lean turkey on whole wheat bread.

7-Eleven, the convenience store chain, is restocking its shelves with an eye toward health. Over the last year, the retailer has introduced a line of fresh foods for the calorie conscious and trimmed down its more indulgent fare by creating portion-size items.

The change is as much about consumers’ expanding waistlines as the company’s bottom line. By 2015, the retailer aims to have 20 percent of sales come from fresh foods in its American and Canadian stores, up from about 10 percent currently, according to a company spokesman.

“We’re aspiring to be more of a food and beverage company, and that aligns with what the consumer now wants, which is more tasty, healthy, fresh food choices,” said Joseph M. DePinto, the chief executive of 7-Eleven, a subsidiary of the Japanese company, Seven & i Holdings.

Convenience stores have typically been among the most nimble of retailers. In the 1980s, they added Pac-Man arcade games as a way to keep customers in stores longer and to buy more merchandise. They installed A.T.M.’s a decade later, taking a slice of the transaction fees. More recently, they built refrigerated dairy cases, with milk, eggs, cheese and other staples.

But just as they have taken business from traditional supermarkets, convenience stores have faced increased competition from the likes of Dunkin’ Donuts and Starbucks, which offer a basic menu of fresh foods for consumers on the go.

At the same time, a major profit driver for convenience stores — cigarettes — has been in steady decline over the last decade as the rate of smoking has dropped in the United States.

Fresh foods can help offset some of those losses. The markup on such merchandise can be significant, bolstering a store’s overall profits. It’s also a fast-growing category.

“If you can figure out how to deliver consistent quality and the products consumers want, fresh food is attractive because margins are higher, and it addresses some of the competitive issues you’re facing,” said Richard Meyer, a longtime consultant for the convenience store industry. “But it’s not easy to do.”

7-Eleven has been selling fresh food since the late 1990s. But much of its innovation has been limited to the variety of hot dogs spinning on the roller grill or the breakfast sandwiches languishing beneath a heating lamp.

As 7-Eleven refocuses its lineup, the retail chain has assembled a team of culinary and food science experts to study industry trends and develop new products. Such groups have been around for a while at fast-food restaurants like McDonald’s and packaged-goods manufacturers like Kraft. But it’s a relatively new concept for players like 7-Eleven, which have typically relied on their suppliers to provide product innovation.

“We’re working to create a portfolio of fresh foods,” said Anne Readhimer, senior director of fresh food innovation, who joined the company in May from Yum Brands, where she had worked on the KFC and Pizza Hut brands. “Some will be for snacking, some for a quick meal, but we hope everything we offer our guests is convenient and tasty.”

One new menu item just hitting stores is a Bistro Snack Protein Pack, which includes mini pita rounds, cheddar cheese cubes, grapes, celery, baby carrots and hummus. The meal in a box, similar to one carried by Starbucks, is part of a broader menu with healthier items under 400 calories.

The company is also taking existing products and retooling them for single portions. For example, customers can now buy jelly doughnuts and tacos, in mini sizes.

“There are definitely customers who want healthy options, but there are also lots of customers who are excited about the new sandwich options that aren’t low calorie — and minidoughnuts are doing very well,” said Lori Primavera, senior manager of fresh food innovation at 7-Eleven, who previously worked for Food and Drink Resources, a consulting firm for restaurant companies.

Norman Jemal, a franchisee, said sales of the new products are growing steadily in the three 7-Eleven stores that he owns in Manhattan. “At first, people are surprised when they come in here and see a bag of carrots and celery,” Mr. Jemal said. “They say, ‘I came in here for a bag of chips — I can’t believe you have fruit cups or yogurt cups.’ ”

He said the Yoplait Parfait, a cup of vanilla yogurt topped with fresh strawberries or blueberries and granola, is his best-selling fresh food item, while the 7 Smart turkey sandwich is his top sandwich.

The fresh food in Mr. Jemal’s stores and other locations around the country are supplied from a system of 29 commissaries and bakeries that fulfill orders from 7-Eleven. They tailor menu items for specific markets. In the Miami area, they produce a hot Cuban sandwich with ham, cheese, pickles and mustard. The Turkey Gobbler with turkey, stuffing and cranberry sauce sells in Northeastern stores around the holidays.

Each store has a data system that allows it to see exactly what is selling, which helps manage waste. Stores can track consumers’ purchase habits over a month, and adjust their orders based on those behaviors.

“In this 28-day cycle, I know I sold 3,563 bananas to customers in this store,” said Todd Ferguson, who owns five 7-Eleven locations in Las Vegas.

Mr. Ferguson has owned 7-Eleven franchises since 1986, and he said the variety of fresh food options in the stores is far better than before. The category already accounts for 20 percent of his sales, and his goal is to reach a quarter of sales volume.

“We used to be a place for people to buy beer, wine, cigarettes, candy and chips, and people would occasionally ask where they could go to get something to eat,” Mr. Ferguson said. “We’re no longer getting that question because now you can get something to eat right here.”

This article has been revised to reflect the following correction:

Correction: December 27, 2012

An earlier version of this article incorrectly identified a 7-Eleven franchisee in Las Vegas. He is Todd Ferguson, not Tom Ferguson.

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Bennett Pushes Netanyahu Rightward

Uriel Sinai/Getty Images

As a major in the army reserves who served in the prestigious Sayeret Matkal unit, then made a fortune in Israel’s booming technology industry, Mr. Bennett embodies one popular vision of today’s Zionist ideal.

JERUSALEM — Naftali Bennett is not a serious contender to be Israel’s next prime minister. He has never held elective office, and the faction he represents currently fills five or seven of Parliament’s 120 seats, depending on how you count.

Yet Mr. Bennett, 40, has emerged a month ahead of the Jan. 22 national elections as perhaps the campaign’s most dynamic and influential factor. Newspaper polls show his revamped Jewish Home party poised to become the third largest in the next Parliament with up to 15 seats, and analysts say Prime Minister Benjamin Netanyahu is running scared as Mr. Bennett’s appealing biography and far-right platform combine to lure voters away from Mr. Netanyahu’s dominant Likud-Beiteinu ticket.

While the prime minister is still widely expected to serve another term, the Bennett phenomenon could transform his governing coalition, balancing — or replacing — the power of the ultra-Orthodox parties with the more nationalist, modern religious sector that has been fractured and weak in the political sphere for decades. Other modern-Orthodox candidates are also ranked high on rival parties’ slates, ensuring their significant numbers in the next Parliament.

“We’re talking about political expression of sociological change in Israeli society,” said Yedidia Z. Stern, a law professor and vice president of the Israel Democracy Institute, a nonpartisan research group. Noting that so-called religious Zionists are ever more prominent in Israel’s military, news media, science and business, Mr. Stern said: “Whatever issue you raise that is a major issue for the state of Israel, the national-religious community has a view that is basically driving the discourse. Bennett is representing it in politics.”

The political tensions over Mr. Bennett’s ascendance intensified in recent days, when Mr. Netanyahu seized on Mr. Bennett’s comment that, as a reserve officer in the Israeli Army, he would refuse an order to evacuate a Jewish settlement in the West Bank on ideological grounds. The prime minister said someone who would refuse had no place in his government. Mr. Bennett quickly recanted, but the attacks have continued.

“Here you see for the first time Netanyahu is really fighting in a serious way someone from the right,” Mr. Stern observed. “I see a real chance that the new coalition will be based on a different kind of transaction.”

Mr. Bennett’s new prominence is one of several forces pushing Mr. Netanyahu rightward. After merging with the ultranationalist Yisrael Beiteinu party, Likud yielded in its primary a far more conservative list than its current Parliament membership, ousting three respected moderates. At the official campaign kickoff on Tuesday evening, there was no mention of a two-state solution to the Israeli-Palestinian conflict — which Mr. Netanyahu has supported — and it is unclear whether the idea will be included in the party platform.

As a major in the army reserve who served in the prestigious Sayeret Matkal unit, then made a fortune in Israel’s booming technology industry, Mr. Bennett embodies one popular vision of today’s Zionist ideal. He wears the knitted kippa that is the religious-Zionist signature but lives in the affluent town of Raanana, north of Tel Aviv — and not in a West Bank settlement — because, he said, his wife is secular.

They have four children, ages 7 to 1, and Mr. Bennett has said he does not believe a solution to the Israeli-Palestinian conflict is achievable in their lifetime.

So, instead of peace, he talks about annexation — as in, Israel should annex the nearly two-thirds of the West Bank known as Area C, which is home to 350,000 Jewish settlers. In his view, the Palestinians who live there — estimates range from Mr. Bennett’s 48,000 to the United Nations’ 150,000 — could then apply for Israeli citizenship, akin to those who live within Israel’s 1948 borders. Then he would try to remove checkpoints to ease traffic and movement throughout the region, and, he said in a recent interview, “make a grocery list of 20 things we could do to make life better” for both Jews and Palestinians living in the territory.

“Forget whether it’s right or wrong; we’re here to stay, now what can we do about it?” he said. “To strive for perfection brings disaster again and again. It’s time for new thinking.

“What do we do in the long term?” he asked, then answered in a way unusual for a politician: “I don’t know.”

The son of San Francisco Bay Area residents who moved to Israel after the 1967 war, Mr. Bennett lived in New York for four years before selling his Internet company, which deals with bank security, in 2005 for $145 million. He was chief of staff to Mr. Netanyahu as leader of the opposition, from 2006 to 2008, then ran the settlers’ council from January 2010 to January 2012.

Irit Pazner Garshowitz contributed reporting.

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Mint, otro Linux para quienes quieren explorar el mundo fuera de Windows

Una de las grandes virtudes de Linux (un sistema operativo libre para PC y otros dispositivos) es la cantidad innumerable de versiones disponibles. Estas distribuciones, además, son en su enorme mayoría de uso gratis, y representan una buena alternativa para los que no desean invertir en una licencia de Windows o quieren explorar -sin gastar- alternativas para la computadora hogareña.

Hemos recomendado en varias ocasiones opciones sencillas de usar e instalar que tienen herramientas iguales o muy similares a las que pueden encontrarse en Windows, destacando la ductilidad de las distribuciones disponibles y cómo hacer para probarlas sin complicarse demasiado , usando un CD regrabable o un pendrive, para no afectar el Windows instalado en la computadora.

En los últimos años fue Ubuntu el que más hizo para facilitarle el trabajo a los neófitos que venían de Windows, automatizando y simplificando procesos de instalación, creando un sitio amigable, sumando instrucciones de instalación y uso en lenguaje no técnico e incluso haciendo acuerdo para preinstalarlo en equipos de marca , pero la elección de la interfaz de usuario Unity (algo rígida) le hizo perder adeptos.

Una de las alternativas que venía creciendo en popularidad era Linux Mint (gratis), y los últimos números de DistroWatch , un sitio que lista las diferentes distribuciones y su popularidad, lo dan como el rey de 2012. Mint usa a Ubuntu como base, por lo que aprovecha algunas de sus herramientas (como la que permite instalarlo dentro de Windows para poder usarlo sin afectar la instalación original) y viene con una gran cantidad de componentes multimedia preinstalados, para facilitar la reproducción de audio y video, entre otras cosas (las distribuciones más “puras” suelen evitar esto para promover el uso de estándares libres de audio y video).

Hace poco más de un mes Linux Mint liberó su versión más reciente, Nadia 14, que incluye dos entornos de escritorio que resultarán muy agradables para quienes no se sienten cómodos con Unity, porque mantienen el esquema tradicional de Windows y Gnome 2.x: una barra de herramientas en la parte inferior de la pantalla, ventanas con los botones de control a la derecha, etcétera.

Linux Mint 14 tiene dos versiones: MATE (basado en Gnome 2.x, y cuyo nombre está inspirado en la yerba mate) y Cinnamon (canela, en inglés) de aspecto similar pero con algunos detalles visuales más atractivos: menús de notificaciones más sofisticados, escritorios virtuales persistentes, miniaturas en el administrador de ventanas y más.

cómo instalarlo

Cualquiera de ellas se puede meter en un pendrive o disco externo y correr desde allí o, si se quiere, instalarlas en la PC, junto con Windows (es compatible con Windows 8) o en una partición nueva. Alcanza con descargar el archivo ISO de instalación (hay uno para MATE y otro para Cinnamon). Ese archivo (900 MB, aproximadamente) se puede grabar en un DVD con una aplicación para quemar imágenes de disco: en Windows está el freeware CDBurnerXP , por ejemplo. Con el disco en la lectora, al encender al PC debería cargar primero Mint antes que Windows (si no, habrá que cambiar una configuración en el BIOS). Podremos usarlo como si estuviera instalado en la PC y luego, si queremos, instalarlo en el disco rígido de nuestra computadora, cuidando de hacerlo en una partición vacía o dentro de Windows.

Otra opción es instalarlo en una memoria USB (de 2 GB o más de capacidad). Para eso hay que usar la aplicación Image Writer (gratis, hay que cliquear donde dice win32diskimager-binary.zip para descargar el archivo). Luego habrá que cambiar la extensión del archivo de .ISO a .IMG para que Image Writer reconozca el archivo y pueda copiarlo en el pendrive (atención que borrará todo lo que está allí).

Si al prender la PC con el pendrive conectado no lo reconoce, habrá que cambiar el orden de carga de sistemas operativos, una opción que suele aparecer apenas se prende la PC (y que no estará disponible si la computadora es muy vieja) para ordenarle que cargue primero el contenido de la memoria USB.

Para quienes estén pensando en probar una distribución de Linux y buscan reducir el “choque cultural” con una interfaz de usuario que sea parecida -pero no idéntica- a la del Windows tradicional, y que además sea sencillo de usar, tienen en Linux Mint 14 Nadia una opción muy atractiva.

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